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Sub-cellular biochemistry/Subcellular Biochem

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High levels of ROS have also been shown to alter the expression patterns of several housekeeping genes, such as FOX3A, NF kappa B, and AP-2

Knock-down of states within the cell can be directly incorporated into the dynamic modeling framework by adjusting the protein production rates of Nrf2, Keap1 and p62 for the corresponding knock-downs